Did You Know: Heart Disease is America 's Number One Killer. It kills an American every 34 seconds but remains a preventable disease. Seventy Million Americans have Heart Disease and 27 Million of them are 65 or older. Unfortunately, younger people are not immune. 150,000 Americans under age 65 die each year from Heart Disease. Many risk factors are preventable or treatable. Keep active, eat healthy, don't smoke, and take care of yourself and get appropriate medical care.